I have just removed the Rear Door Seal from my 2005 GXL (cleaning out the red dust).
This is the first time this seal has been removed and there was dust collected inside the seal but only from window level up, the dust does not leak into the car,
no water either,I was surprised at how easy it was to get the seal off.
The problem is I have found several small areas of rust along the edge of the spotwelded flange that the seal fits onto, this is only along the bottom edge.
I will trot along to Toyota on Monday to have them look at it, and will post the results.